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Thyroid health

thyroid basics

Thyroid basics — what you need to know

Reviewed by Dixie Mills, MD, Marcelle Pick, OB/GYN NP and Mary James, ND

You probably know that the thyroid gland is important for weight control and overall wellness, but many women we talk with aren’t exactly sure what the thyroid does and how it connects to the way they feel every day.

Low thyroid function, or hypothyroidism, is the most common form of thyroid imbalance. Symptoms of low thyroid can include fatigue, poor concentration, constipation, weight gain, skin issues, dry, coarse, or thinning hair or hair loss, and even depression. Women often call us because they’re experiencing some of these symptoms, but have been told by their doctors that “everything looks fine.” The fact is, thyroid-related issues can arise at any age and may not necessarily show up on routine lab tests.

But my doctor says my thyroid results are normal...

In our experience, the ‘normal’ lab ranges for thyroid function that are used in conventional medicine are not specific enough to identify subclinical problems.

For example, most conventional medicine labs set the ‘normal’ range for TSH as typically between 0.4 to 4.0 mIU/L, but we like to see TSH stay as close to 2.0 mIU/L as possible; a higher level can indicate low thyroid function in many women. Ideally, we like your thyroid levels to stay in the middle of these ranges, rather than at either end of the extremes. We also often look at a patient’s trends in thyroid function to see if her levels are creeping up or down over time. And we always pay attention to the specific symptoms a patient reports.

The good news is that natural thyroid support is available, and effective.

Though they can vary from lab to lab, typical thyroid ranges in the blood are:

  • T4: 4.8–13.2 mcg/dL
  • Free T4: 0.9–2 ng/dL
  • T3: 80–200 ng/dL
  • TSH: 0.4–4.0 mIU/L (if you have no hypothyroid or hyperthyroid symptoms)
    0.3–3.0 mIU/L (if you’re being treated with thyroid hormone)

It’s important to understand the basics so that you’ll know how to best support your thyroid health at every point in your life.

What does the thyroid do?

Centrally located at the base of the throat, between the brain and rest of the body, the butterfly-shaped thyroid gland helps maintain overall balance in the body. Its hormones affect many systems and functions, including:

  • Metabolism
  • Brain development
  • Breathing, heart and nervous system function
  • Blood cell production
  • Muscle and bone strength
  • Body temperature
  • Menstrual cycles
  • Weight gain and loss
  • Cholesterol levels
  • Skin hydration

Your thyroid helps determine how you metabolize food, how you store and use energy, how you think, talk, sleep and more! So it makes sense that when your thyroid isn’t functioning properly, your life can seem significantly off-kilter.

The hormones of the thyroid, thyroxine (T4) and triiodothyronine (T3), influence the metabolism of each and every cell in our bodies. T3 is the thyroid hormone that our cells recognize best; it is actually the only biologically active thyroid hormone in the body. T4 can be thought of as a “preparatory” hormone for T3; T4 is converted into T3 in the liver and kidneys.

The conversion process of thyroid hormone is a series of events. When T3 and T4 are low in the bloodstream, the part of your brain known as the hypothalamus — the “command center” for most hormones — sends a message in the form of TRH (thyrotropin-releasing hormone) to the pituitary gland. Functioning as a sort of “halfway house” between the brain and the endocrine system, the pituitary gland interprets the message to secrete more TSH (thyroid-stimulating hormone), which in turn, prompts your thyroid gland to take up iodine and the amino acid, tyrosine, to produce more T3 and T4. If your thyroid hormones range too high, the hypothalamic and pituitary signals become much quieter until your thyroid hormones are in balance again.

thyroid basics

With its elegant system of checks and balances, your body has the natural tendency to restore thyroid balance. So as long as your hormonal system is fairly well balanced and your thyroid is properly supported, it will generally move toward its default “normal” state. This support becomes increasingly important as we age.

Common thyroid imbalances

Hypothyroidism

When your thyroid hormones are too low to support your daily activities, it is known as hypothyroidism. This can be due to either inadequate production of T4 in your thyroid gland, or poor conversion of T4 to the more active T3 hormone. Hypothyroidism can cause severe fatigue and loss of energy, dry skin, hair changes, general puffiness, constipation, cold intolerance, and more. It can also increase cholesterol levels and aggravate issues like PMS, menstrual irregularities, and fibrocystic breasts.

The most common cause of hypothyroidism is an autoimmune disease called Hashimoto’s thyroiditis. Sometimes women with autoimmune thyroiditis go back and forth between hyperthyroidism and hypothyroidism.

Hyperthyroidism

When the thyroid produces too much thyroid hormone, it is called hyperthyroidism. Too much thyroid hormone can cause nervousness and anxiety, increased heart rate or palpitations, breathlessness, diarrhea, insomnia, and depression.

The most common cause of hyperthyroidism is an autoimmune disease called Graves’ disease. Chronic Graves’ disease may cause a person’s eyes to bulge (exophthalmos). For more on symptoms and causes, see our page on hyperthyroidism.

Subclinical hypothyroidism

When someone experiences symptoms of hypothyroidism even though her thyroid test results are still in the “normal range,” it’s probable that her lab tests are at either extreme end of the normal range. This is called subclinical hypothyroidism. Despite having what’s considered “normal” lab test results, people in this category often feel much better when their thyroid function is enhanced.

Because thyroid imbalances and related disorders typically occur along a continuum, it’s a good idea to track both your lab work and your symptoms.

Thyroid imbalances are common during hormonal flux

Because the thyroid and ovaries are connected by a feedback loop in the brain, periods of naturally-shifting hormones can cause disturbances in the thyroid.

Pregnancy. During a healthy pregnancy, estrogen and the pregnancy hormone hCG (human chorionic gonadotropin) cause increased thyroid hormone levels in our blood. Because of the natural shifting of hormones during this time, hypothyroidism and/or hyperthyroidism can occur during or after pregnancy.

Perimenopause. As we begin the journey toward menopause, estrogen, progesterone, and testosterone are in flux. This fluctuation can affect messages sent to the brain regarding thyroid hormones. As we produce less estrogen, thyroid-releasing hormone (TRH) can also slow down, resulting in less available T3 and T4 for our cells.

Periods of stress. The thyroid gland can be affected when we’re under stress because of its connection to the adrenal glands (our stress responders). During periods of chronic stress, the adrenal glands pump out the stress hormones, cortisol and adrenalin. Although these hormones help our bodies adapt to stress, they can also inhibit thyroid stimulating hormone (TSH) and the conversion of T4 into the more active thyroid hormone, T3. The result is low thyroid function.

Supporting your thyroid naturally

thyroid basics

Given the importance of the thyroid and its responsibilities in your body, it’s surprisingly easy to provide support in your daily life. Here are the three most important areas:

Food for your thyroid. Food plays an essential role in every day thyroid function. First of all, make a point of eating breakfast every day, so that your system gets a balanced start. Keep sweets and simple starches to a minimum and make sure that you get enough protein. Too many carbs and too little protein can both interfere with the conversion of T4 into T3. Your thyroid also requires specific nutrients for proper functioning, such as iodine, selenium and other minerals, tyrosine, and B vitamins. Some of these nutrients are available in seafood and sea vegetables, as well as poultry, Brazil nuts, mushrooms, legumes, yogurt, strawberries, and eggs. See our chart on whole foods to support your thyroid.

Herbs and minerals to support healthy thyroid function. Herbs like ashwagandha, hops, sage, bacopa monnieri, coleus, and guggul can also help support thyroid hormone production and balance hormonal signals to the thyroid gland, thus boosting energy and protecting other functions in the body.

Thyroid-healthy lifestyle changes. You might not expect that factors like managing stress, taking time for yourself, getting enough sleep, exercising regularly, and attending to emotional wellness would make a significant difference when it comes to thyroid health — but they can. So can getting out in the sun for a bit each day (to help maintain adequate vitamin D levels) and avoiding exposure to herbicides, pesticides, and cigarette smoke. These steps can also support your adrenal glands, which are intimately connected to thyroid health.

We’ve made it even easier for you to take care of your thyroid with our Personal Program for Thyroid Support. With shopping lists of thyroid-supporting foods, suggestions for appropriate lifestyle changes, and an herbal supplement scientifically formulated with iodine, selenium, hops, sage, and other thyroid-supporting herbs, you can cover all the basic physiological needs of your thyroid on a consistent basis.

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References:

Norman Endocrine Surgery Clinic. 2005. How your thyroid works. URL: http://www.endocrineweb.com/thyfunction.html.

Lombard, J. 2005. Chapter 32. Clinical approaches to hormonal and neuroendocrine imbalances. Section VI: Neurotransmitters: A functional medicine approach to neuropsychiatry. In Textbook of Functional Medicine, ed. D. Jones & S. Quinn, 644. Gig Harbor, WA: Institute for Functional Medicine.

National Endocrine and Metabolic Diseases Information Service. 2008. Pregnancy and thyroid disease. URL: http://endocrine.niddk.nih.gov/pubs/pregnancy/.

 

Last Modified Date: 03/29/2012
Reviewed by Dixie Mills, MD and Marcelle Pick, OB/GYN NP


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