Hormone replacement therapy
How often should I use my estradiol gel product, and where should I apply it?
Q: I was recommended to use a topical gel form of estradiol, but I’m not sure how
often is too often to use it, or where I should apply it for the best effects. Does
it make a difference where I use it?
A: Topical estradiol products (gels, mists, creams) are typically applied once or
twice daily. The makers of Estrogel, Estrasorb, Divigel, Elestrin, and Evamist all
suggest applying the product on the arms. Estrogel can also be applied to the thighs.
The main reason these sites are recommended is because that is where they were used
during the product studies; it doesn’t mean they won’t work if applied elsewhere,
only that these sites are known to be effective, whereas others have not been studied.
Out of an abundance of caution, topical hormones should never be applied to the
breast or skin that is irritated, and most of these products are not designed to
be applied to the genitals.
Even if you’re too busy, please don’t forget to read the product insert. Be sure
to do this every time you refill your prescription, too — there may be important
new information there!
Our Personal Program is a great place to start
The Personal Program promotes natural hormonal balance with nutritional supplements,
our exclusive endocrine support formula, dietary and lifestyle guidance, and optional
phone consultations with our Nurse–Educators. It is a convenient, at-home
version of what we recommend to all our patients at the clinic.
If you have questions, don't hesitate to call us toll-free at
1-800-798-7902. We're here to listen and help.
We’re always happy to welcome new patients to our medical clinic in Yarmouth,
Maine, for those who can make the trip. Click
here for information about making an appointment.
Related to this article:
References & further reading for FAQ’s about
HRT
Original Publication Date: 03/02/2009
Last Modified:
02/16/2010
Principal Author: Marcy Holmes, NP, Certified Menopause Clinician