Hormone replacement therapy
How often should I use the estradiol gel products, and where should I apply them?
Q: I was prescribed a gel form of estradiol, and I’m not sure how often is too often, or where I should apply it for the best effects. Does it make a difference where I use it?
A: Topical estradiol products (gels, mists, creams) are typically applied once or twice daily. The makers of EstroGel, Evamist, and Divigel all suggest applying the product on the arms. EstroGel can also be applied to the thighs. The reason that these sites are recommended is because that is where they were used during the product studies; it doesn’t mean they won’t work if applied elsewhere, only that these sites are known to be effective, whereas others have not been studied.
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Our Personal Program is a great place to start
The Personal Program promotes natural hormonal balance with nutritional supplements, our exclusive endocrine support formula, dietary and lifestyle guidance, and optional phone consultations with our Nurse–Educators. It is a convenient, at-home version of what we recommend to all our patients at the clinic.
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Related to this article:
References & further reading for FAQ’s about HRT
Original Publication Date: 03/02/2009
Last Modified: 08/17/2009
Principal Author: Marcy Holmes, NP, Certified Menopause Clinician