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Depression, anxiety & mood

Antidepressants and natural treatment alternatives — References & further reading

References

1 Mojtabai, R. 2008. Increase in antidepressant medication in the US adult population between 1990 and 2003. Psychother. Psychosom., 77 (2), 83–92 URL: http://content.karger.com/produktedb/produkte.asp?typ=fulltext&file=000112885 (accessed 03.22.2010).

2 Barber, C. 2008. The medicated Americans: Antidepressant prescriptions on the rise. Scientific American. URL: http://www.scientificamerican.com/article.cfm?id=the-medicated-americans (accessed 04.08.2010).

3 MacReddy, N. 2007. Antidepressant metabolite for menopause symptoms. URL: http://www.medscape.com/viewarticle/556290 (accessed 04.08.2010).

  Beasley, D. 2007. Wyeth’s Pristiq helps menopause hot flashes —trials. URL: http://www.reuters.com/article/idUSN0136556020070508 (accessed 04.08.2010).

4 Warner Chilcott. [No date of publication listed.] Sarafem. URL: http://www.wcrx.com/products/sarafem.jsp (accessed 04.08.2010).

5 Lacasse, J., & Leo, J. 2005. Serotonin and depression: A disconnect between the advertisements and the scientific literature. PLoS Med., 2 (12), e392. URL: http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.0020392 (accessed 04.08.2010).

  [No author listed.] 2005. Ads for SSRI antidepressants are misleading, say researchers. Medical News Today. URL: http://www.medicalnewstoday.com/articles/33290.php (accessed 04.08.2010).

6 Morgan, A., & Jorm, A. 2008. Self-help interventions for depressive disorders and depressive symptoms: A systematic review. Ann. Gen. Psychiatry, 7, 13, URL: http://www.annals-general-psychiatry.com/content/7/1/13 (accessed 04.08.2010).

7 [No author listed]. 2009. New data shows overreliance on antidepressants, says Mental Health Foundation. URL: http://www.mentalhealth.org.uk/media/news-releases/news-releases-2009/21-april-2009/ (accessed 04.08.2010).

8 Jones, N. 2008. Antidepressants “no better than placebo.” The Great Beyond. URL: http://blogs.nature.com/news/thegreatbeyond/2008/02/post_3.html (accessed 04.08.2010).

  Moncrieff, J., et al. 2004. Active placebos versus antidepressant for depression. Cochrane Database Syst. Rev., 1, CD003012. URL: http://www.ncbi.nlm.nih.gov/pubmed/14974002 (accessed 04.08.2010).

  Kirsch, I., et al. 2002. The emperor’s new drugs: An analysis of antidepressant medication data submitted to the U.S. Food and Drug Administration. Prev. Treat., 5, article 23. URL: http://journals.apa.org/prevention/volume5/pre0050023a.html (accessed 04.08.2010).

  Kirsch, I., et al. 2002. Antidepressants and placebos: Secrets, revelations, and unanswered questions. Prev. Treat., 5, article 33. URL: http://journals.apa.org/prevention/volume5/pre0050033r.html (accessed 04.08.2010).

9 Fournier, J., et al. 2010. Antidepressant drug effects and depression severity. JAMA, 303 (1), 47–53. URL: http://jama.ama-assn.org/cgi/content/short/303/1/47?home (accessed 01.16.2010).

10 [No author listed.] 2006. Some can’t stop antidepressants. URL: http://www.msnbc.msn.com/id/14126142 (accessed 04.08.2010).

11 Attar–Herzberg, D., et al. 2009. The serotonin syndrome: Initial misdiagnosis. Isr. Med. Assoc. J., 11 (6), 367–370. URL (abstract): http://www.ima.org.il/imaj/dynamic/web/ArtFromPubmed.asp?year=2009&month=06&page=367 (accessed 04.08.2010).

  Dvir, Y., & Smallwood, P. 2008. Serotonin syndrome: A complex but easily avoidable condition. Gen. Hosp. Psychiatry, 30 (3), 284–287. URL: http://www.ncbi.nlm.nih.gov/pubmed/18433663 (accessed 04.08.2010).

12 Lehrer, J. 2010. Depression’s upside. NYTimes.com. URL: http://www.nytimes.com/2010/02/28/magazine/28depression-t.html (accessed 03.22.2010).

13 Cowan, P. 2002. Cortisol, serotonin and depression: All stressed out? Br. J. Psych., 180 (2), 99–100. URL: http://bjp.rcpsych.org/cgi/content/full/180/2/99 (accessed 03.22.2010).

14 Shenassa, E., et al. 2007. Dampness and mold in the home and depression: An examination of mold-related illness and perceived control of one’s home as possible depression pathways. Am. J. Public Health, 97 (10), 1893–1899. URL: http://ajph.aphapublications.org/cgi/content/full/97/10/1893?view=long&pmid=17761567 (accessed 04.08.2010).

  Keates, N. 2007. The unmedicated mind. Wall Street Journal. URL: http://online.wsj.com/article/SB118428285736265304.html (accessed 03.22.2010).

15 Zelissen, P., et al. 1991. Beta-endorphin and insulin/glucose responses to different meals in obesity. Horm. Res., 36 (1–2), 32–35. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/1814798 (accessed 04.08.2010).

16 Hays, B. 2005. Chapter 19. Hormonal imbalances: Female hormones: The dance of the hormones. Pt. I. In Textbook of Functional Medicine, 228–229. Gig Harbor, WA: Institute for Functional Medicine.

17 Vieth, R., et al. 2004. Randomized comparison of the effects of the vitamin D3 adequate intake versus 100 mcg (4000 IU) per day on biochemical responses and the wellbeing of patients. Nutrition J., 3 (1), 8. URL: http://www.nutritionj.com/content/3/1/8 (accessed 05.27.2006).

  Lansdowne, A., & Provost, S. 1998. Vitamin D3 enhances mood in healthy subjects during winter. Psychopharmacology (Berl.), 135 (4), 319–323. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/9539254 (accessed 05.27.2006).

18 Annesi, J. 2005. Changes in depressed mood associated with 10 weeks of moderate cardiovascular exercise in formerly sedentary adults. Psychol. Rep., 96 (3 pt. 1), 855–862. URL: (accessed 03.23.2010)

  Mather, A., et al. 2002. Effects of exercise on depressive symptoms in older adults with poorly responsive depressive disorder: randomised controlled trial. Br. J. Psychiatry, 180 (5), 411–415. URL: http://bjp.rcpsych.org/cgi/content/full/180/5/411 (accessed 03.23.2010).

  Blumenthal, J., et al. 1999. Effects of exercise training on older patients with major depression. Arch. Intern. Med., 159, 2349–2356. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/10547175 (accessed 03.23.2010).

19 NeuroScience. 2010. Chapter 7. Addressing neurotransmitter imbalances. https://www.neurorelief.com/index.php?option=com_content&task=view&id=133&Itemid=48 (accessed 03.23.2010).

  Meyers, S. 2000. Use of neurotransmitter precursors for treatment of depression. Alt. Med. Rev., 5 (1), 64–71. URL (PDF): http://www.thorne.com/altmedrev/.fulltext/5/1/64.pdf (accessed 09.02.2008).

20 Papakostas, G. 2009. Evidence for S-adenosyl-L-methionine (SAM-e) for the treatment of major depressive disorder. J. Clin. Psychiatry, 70 (Suppl. 5), 18-22. URL: http://www.ncbi.nlm.nih.gov/pubmed/19909689 (accessed 03.23.2010).

  Papakostas, G., et al. 2003. S-adenosyl-methionine in depression: A comprehensive review of the literature. Curr. Psychiatry Rep., 5 (6), 460–466. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/14609501 (accessed 03.24.2010).

  Young, S. 2003. Are SAMe and 5-HTP safe and effective treatments for depression? J. Psychiatry Neurosci., 28 (6), 471. URL: http://www.ncbi.nlm.nih.gov/pubmed/16023217 (accessed 03.24.2010).

  Meyers, S. 2000.

21 Lynn–Bullock, C., et al. 2004. The effect of oral 5-HTP administration on 5-HTP and 5-HT immunoreactivity in monoaminergic brain regions of rats. J. Chem. Neuroanat., 27 (2), 129-138. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/15121217 (accessed 03.24.2010).

  Young, S. 2003.

  Shaw, K., et al. 2002. Tryptophan and 5-hydroxytryptophan for depression. Cochrane Database Syst. Rev. (1), CD003198. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/11869656 (accessed 10.07.2008).

  Birdsall, T. 1998. 5-Hydroxytryptophan: A clinically-effective serotonin precursor. Altern. Med. Rev., 3 (4), 271–280 (PDF). URL: http://www.thorne.com/altmedrev/.fulltext/3/4/271.pdf (accessed 03.24.2010).

22 Appleton, K., et al. 2010. Updated systematic review and meta-analysis of the effects of n-3 long-chain polyunsaturated fatty acids on depressed mood. Am. J. Clin. Nutr., 91 (3), 757–770. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20130098 (accessed 03.23.2010).

CONCLUSIONS: Trial evidence of the effects of n-3 PUFAs on depressed mood has increased but remains difficult to summarize because of considerable heterogeneity. The evidence available provides some support of a benefit of n-3 PUFAs in individuals with diagnosed depressive illness but no evidence of any benefit in individuals without a diagnosis of depressive illness.

23 Rastad, C., et al. 2008. Light room therapy effective in mild forms of seasonal affective disorder — a randomised controlled study. J. Affect. Disord., 108 (3), 291-296. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/18053580 (accessed 03.25.2010).

  Desan, P., et al. 2007. A controlled trial of the Litebook light-emitting diode (LED) light therapy device for treatment of Seasonal Affective Disorder (SAD). BMC Psychiatry, 7, 38. URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971065/?tool=pubmed (accessed 03.25.2010).

  Gloth, F., et al. 1999. Vitamin D vs. broad-spectrum phototherapy in the treatment of seasonal affective disorder. J. Nutr. Health Aging, 3, 5–7. URL: http://www.ncbi.nlm.nih.gov/pubmed/10888476 (accessed 03.25.2010).

  Partonen, T., et al. 1996. Effects of bright light on sleepiness, melatonin, and 25-hydroxyvitamin D3 in winter seasonal affective disorder. Biol. Psychiatry, 39 (1), 865–872. URL: http://www.ncbi.nlm.nih.gov/pubmed/9172707 (accessed 03.25.2010).

  Oren, D., et al. 1994. 1,25(OH)2 vitamin D3 levels in seasonal affective disorder: Effects of light. Psychopharmacology (Berl)., 116 (4), 515–516. URL: http://www.ncbi.nlm.nih.gov/pubmed/7701056 (accessed 03.25.2010).

24 Stein, J. 2010. Depression symptoms may lift with Transcendental Meditation. URL: http://latimesblogs.latimes.com/booster_shots/2010/04/depression-symptoms-may-lift-with-transcendental-meditation.html (accessed 04.08.2010).


Nutrients to enhance mood — References

a Hinz, M. 2009. “Depression.” In Foods and Nutrients in Disease Management, ed. I Kohlstadt. Boca Raton, FL: CRC Press.

  DesMaisons, K. 2008. Potatoes Not Prozac: Solutions for Sugar Sensitivity, 141. [Revised edition.] NY: Simon & Schuster.

  Lombard, J. 2005. Chapter 32. Clinical approaches to hormonal and neurotransmitter imbalances. Pt. I. In Textbook of Functional Medicine, 638–644. Gig Harbor, WA: Institute for Functional Medicine.

b DesMaisons, K. 2008. Potatoes Not Prozac: Solutions for Sugar Sensitivity, 141. [Revised edition.] NY: Simon & Schuster.

c Murphy, P., & Wagner, C. 2008. Vitamin D and mood disorders among women: An integrative review. J. Midwifery Women’s Health, 53 (5), 440–446. URL: http://www.medscape.com/viewarticle/579946 (accessed 03.25.2010).

  Dumville, J., et al. 2006. Can vitamin D supplementation prevent winter-time blues? (A randomised trial among older women.) J. Nutr. Health Aging, 10 (2), 151–153. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/16554952 (accessed 04.08.2010).

  Obradovic, K., et al. 2006. Cross-talk of vitamin D and glucocorticoids in hippocampal cells. J. Neurochem., 96, 500–509. URL (PDF): http://assets0.pubget.com/pdf/16336217.pdf (accessed 03.25.2010).

  Bertone-Johnson, E., et al. 2005. Calcium and vitamin D intake and risk of incident premenstrual syndrome. Arch. Intern. Med., 165, 1246–1252. URL (abstract): (accessed 04.08.2010).

  Lansdowne, A., & Provost, S. 1998. Vitamin D3 enhances mood in healthy subjects during winter. Psychopharmacology (Berl.), 135, 319–323. URL: http://www.ncbi.nlm.nih.gov/pubmed/9539254 (accessed 04.08.2010).

  Oren, D., et al. 1994. 1,25(OH)2 vitamin D3 levels in seasonal affective disorder: Effects of light. Psychopharmacology (Berl.), 116, 515–516. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/7701056 (accessed 04.08.2010).

  Partonen, T., et al. 1996. Effects of bright light on sleepiness, melatonin, and 25-hydroxyvitamin D3 in winter seasonal affective disorder. Biol. Psychiatry, 39, 865–872. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/9172707 (accessed 04.08.2010).

  Wilkins, C. 2006. Vitamin D deficiency is associated with low mood and worse cognitive performance in older adults. Am. J. Geriatr. Psychiatry, 14 (12), 1032–1040. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/17138809 (accessed 03.25.2010).

d Lombard, J. 2005.

e [No author listed.] 2005. l-theanine. Monograph. Altern. Med. Rev., 10 (2), 136–138. URL (PDF): http://www.thorne.com/altmedrev/.fulltext/10/2/136.pdf (accessed 04.08.2010).

f Hinz, M. 2009. “Depression.” In Foods and Nutrients in Disease Management, ed. I Kohlstadt. Boca Raton, FL: CRC Press.

g Sawada, T., & Yokoi, K. 2010. Effect of zinc supplementation on mood states in young women: A pilot study. Eur. J. Clin. Nutr., 64 (3), 331–333. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20087376 (accessed 04.08.2010).

  DesMaisons, K. 2008. Potatoes Not Prozac: Solutions for Sugar Sensitivity, 141. [Revised edition.] NY: Simon & Schuster.

  Hays, B. 2005. Chapter 19. Hormonal imbalances: Female hormones: The dance of the hormones. Pt. I. In Textbook of Functional Medicine, 228–229. Gig Harbor, WA: Institute for Functional Medicine.

Further reading

Weiner, P. 2007. The US managed care / health insurance industry: A fact sheet & glossary of terms (2007). URL (PDF): http://ocw.jhsph.edu/courses/managedcare/PDFs/MC%20FACT%20SHEET.pdf (accessed 11.05.2007).

Annesi, J. 2005. Changes in depressed mood associated with 10 weeks of moderate cardiovascular exercise in formerly sedentary adults.  Psychol. Rep., 96 (3 pt. 1), 855–862.

Fava, M., et al. 2005. A double-blind, randomized trial of St. John’s wort, fluoxetine, and placebo in major depressive disorder. J. Clin. Psychopharm., 25 (5), 441–447. URL:  http://www.psychopharmacology.com/pt/re/jclnpsychopharm/abstract.00004714-200510000-00007.htm (accessed 11.21.2005).

Oswald, P., et al. 2005. Predictive factors of resistance to antidepressant treatment: Results from a European multicenter study. Abstract S.07.07. Presented at the 18th Congress of the European College of Neuropsychopharmacology (ECNP), Amsterdam.

Paton, C., & Ferrier, I. 2005. SSRIs and gastrointestinal bleeding (Editorial). BMJ, 331 (7516), 529–530.

United Kingdom Parliament. 2005. House of Commons health report. London: United Kingdom House of Commons. URL: http://www.publications.parliament.uk/pa/cm200405/cmselect/cmhealth/42/4202.htm (accessed 11.21.2005).

Meijer, W., et al. 2004. Association of risk of abnormal bleeding with degree of serotonin reuptake inhibition by antidepressants. Arch. Intern. Med., 164 (21), 2367–2370.

Rosack, J. 2004. Data fail to answer key question about SSRIs’ suicide risk. Psychiatric News, 39 (6), 2. URL: http://pn.psychiatryonline.org/cgi/content/full/39/6/2 (accessed 11.20.2005).

No author listed. 2004. SSRI, suicide link called weak. Psychiatric News, 39 (5), 63. URL: http://pn.psychiatryonline.org/cgi/content/full/39/5/63 (accessed 11.20.2005).

Bjorkman, D. 2003. SSRI’s and upper GI bleeding: Depressing news? J. Watch Gastroenterology, 1.

Dalton, S., et al. 2003. Use of selective serotonin reuptake inhibitors and risk of upper gastrointestinal tract bleeding: A population-based cohort study. Arch. Intern. Med., 163 (1), 59–64.

Mintzes, B. et al. 2003. How does direct-to-consumer advertising (DTCA) affect prescribing? A survey in primary care environments with and without legal DTCA. CMAJ, 169, 405–412.

Tucker, G. 2003. SSRI’s and risk for GI bleeding. J. Watch Psychiatry, 1–1.

Barrett, J., et al. 2001. Treatment of dysthymia and minor depression in primary care: A randomized trial in patients aged 18 to 59 years. J. Fam. Pract., 50, 405–412.

Croghan, T. 2001. The controversy of increased spending for antidepressants.  Health Aff., 20 (2), 129–135.

Quitkin, F.,  2000. Validity of clinical trials of antidepressants. Am. J. Psychiatry, 157, 327–337.

Horgan, J. 1999. Placebo nation. NY Times. URL: http://query.nytimes.com/gst/health/article-page.html?res=9C00E3D61531F932A15750C0A96F958260 (accessed 11/19/2005).

Way, K., et al. 1999. Antidepressant utilization patterns in a managed care organization. Drug Benefit Trends, 11 (9), 6BH–11BH.

Elkin, I., et al. 1995. Initial severity and differential treatment outcome in the National Institute of Mental Health Treatment of Depression Collaborative Research Program. J. Consult. Clin. Psychol., 63, 841–847.

Greenberg, R., et al. 1994. A meta-analysis of fluoxetine outcome in the treatment of depression, J. Mental & Nervous Disorders, 182 (10), 547–551.

Agency for Health Care Policy and Research. 1993. Clinical Practice Guideline Number 5: Depression in Primary Care, 2: Treatment of Major Depression. AHCPR publication 93-0551. Rockville, MD: US DHHS.

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